Progress in the Synthesis and Modification of Glass Surfaces Necessary to the Study of Single Molecule Protein Folding and Nanolithography

Engebretson, David Alan
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http://hdl.handle.net/2142/84210

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Title:Progress in the Synthesis and Modification of Glass Surfaces Necessary to the Study of Single Molecule Protein Folding and Nanolithography
Author(s):Engebretson, David Alan
Doctoral Committee Chair(s):McDonald, J. Douglas
Department / Program:Chemistry
Discipline:Chemistry
Degree Granting Institution:University of Illinois at Urbana-Champaign
Degree:Ph.D.
Genre:Dissertation
Subject(s):Biophysics, General
Abstract:The focus of this research was to monitor the folding of a single protein molecule using sp-FRET. In order to accomplish this task, surface modification of a glass coverslip was necessary to prevent non-specific binding. Modification of the surface was accomplished by derivatizing the surface with PEG's and dextrans. Also, the surface was modified using a metal coated AFM tip, resulting in nanolithography of the surface which was observed using confocal microscopy.
Issue Date:2005
Type:Text
Language:English
Description:114 p.
Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 2005.
URI:http://hdl.handle.net/2142/84210
Other Identifier(s):(MiAaPQ)AAI3202088
Date Available in IDEALS:2015-09-25
Date Deposited:2005


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