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Description
Title: | Progress in the Synthesis and Modification of Glass Surfaces Necessary to the Study of Single Molecule Protein Folding and Nanolithography |
Author(s): | Engebretson, David Alan |
Doctoral Committee Chair(s): | McDonald, J. Douglas |
Department / Program: | Chemistry |
Discipline: | Chemistry |
Degree Granting Institution: | University of Illinois at Urbana-Champaign |
Degree: | Ph.D. |
Genre: | Dissertation |
Subject(s): | Biophysics, General |
Abstract: | The focus of this research was to monitor the folding of a single protein molecule using sp-FRET. In order to accomplish this task, surface modification of a glass coverslip was necessary to prevent non-specific binding. Modification of the surface was accomplished by derivatizing the surface with PEG's and dextrans. Also, the surface was modified using a metal coated AFM tip, resulting in nanolithography of the surface which was observed using confocal microscopy. |
Issue Date: | 2005 |
Type: | Text |
Language: | English |
Description: | 114 p. Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 2005. |
URI: | http://hdl.handle.net/2142/84210 |
Other Identifier(s): | (MiAaPQ)AAI3202088 |
Date Available in IDEALS: | 2015-09-25 |
Date Deposited: | 2005 |
This item appears in the following Collection(s)
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Dissertations and Theses - Chemistry
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Graduate Dissertations and Theses at Illinois
Graduate Theses and Dissertations at Illinois