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Title:Protein -Lipid Interactions in Soluble Nanoscale Lipid Bilayers
Author(s):Shaw, Andrew W.
Doctoral Committee Chair(s):Sligar, Stephen G.
Department / Program:Chemistry
Discipline:Chemistry
Degree Granting Institution:University of Illinois at Urbana-Champaign
Degree:Ph.D.
Genre:Dissertation
Subject(s):Chemistry, Biochemistry
Abstract:Finally, a method to rapidly pattern and assay Nanodiscs using microfluidics was developed. The technique uses microfluidic channels to pattern rows of Nanodiscs on a glass slide, and then deliver multiple analytes in perpendicular rows to create a "matrix" assay. This successfully characterized the binding of steptavidin to biotinylated lipids and annexin to phosphoserine lipids in Nanodiscs.
Issue Date:2007
Type:Text
Language:English
Description:120 p.
Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 2007.
URI:http://hdl.handle.net/2142/84265
Other Identifier(s):(MiAaPQ)AAI3270025
Date Available in IDEALS:2015-09-25
Date Deposited:2007


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