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Title:I. Synthetic Approaches Towards 2-Fluoroestradiol. II. Synthesis and Evaluation of Tacn-Rhenium Complexes as Estrogen Receptor Imaging Agents
Author(s):Nickels, Michael
Doctoral Committee Chair(s):Katzenellenbogen, John A.
Department / Program:Chemistry
Discipline:Chemistry
Degree Granting Institution:University of Illinois at Urbana-Champaign
Degree:Ph.D.
Genre:Dissertation
Subject(s):Chemistry, Organic
Abstract:While imaging ER levels in tumors can be done using F-18 labeled estrogens it is important to develop receptor imaging agents labeled with the widely available and less expensive technetium-99m radionuclide. We have explored the synthesis and evaluation of metal carbonyl complexes with 1,4,7-triazacyclononane. The results have suggested that these complexes are not suitable for ER imaging.
Issue Date:2007
Type:Text
Language:English
Description:133 p.
Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 2007.
URI:http://hdl.handle.net/2142/84275
Other Identifier(s):(MiAaPQ)AAI3290334
Date Available in IDEALS:2015-09-25
Date Deposited:2007


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