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Title:Separation and Structure Characterization of Biologically Important Substances
Author(s):Kong, Zhengrong
Doctoral Committee Chair(s):Rinehart, Kenneth L., Jr.; Bohn, Paul W.
Department / Program:Chemistry
Discipline:Chemistry
Degree Granting Institution:University of Illinois at Urbana-Champaign
Degree:Ph.D.
Genre:Dissertation
Subject(s):Chemistry, Pharmaceutical
Abstract:An attempt was made to isolate urease inhibitors from commercial Yucca schidigera extract. Trans-3,3$\sp\prime$,5,5$\sp\prime$- tetrahydroxy-4-methoxystilbene was isolated and its structure was assigned. Biological tests indicated that it was a urease inhibitor, and that it was also active against the L1210 murine leukemia cell line. The enzymatic assay indicated, however, that Cu$\sp{2+}$ (CuSO$\sb4$), which is one of the additives in the commercial Yucca schidigera extract, showed potent urease inhibition activity.
Issue Date:1998
Type:Text
Language:English
Description:252 p.
Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 1998.
URI:http://hdl.handle.net/2142/84399
Other Identifier(s):(MiAaPQ)AAI9834702
Date Available in IDEALS:2015-09-25
Date Deposited:1998


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