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Title:Functional and Mechanistic Investigations of Enzymes in the Enolase Superfamily
Author(s):Hubbard, Brian Kent
Doctoral Committee Chair(s):Gerlt, John A.
Department / Program:Chemistry
Discipline:Chemistry
Degree Granting Institution:University of Illinois at Urbana-Champaign
Degree:Ph.D.
Genre:Dissertation
Subject(s):Chemistry, Organic
Abstract:In this thesis, the enolase superfamily is traced phylogentically and studied in detail to ascertain which active site residues are necessary to maintain function, kinetic competence, and/or substrate specificity. Methods for understanding the details of many enzymes in the enolase superfamily are developed as well as methods for predicting the function of previously uncharacterized members of the enolase superfamily.
Issue Date:2000
Type:Text
Language:English
Description:165 p.
Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 2000.
URI:http://hdl.handle.net/2142/84465
Other Identifier(s):(MiAaPQ)AAI9955627
Date Available in IDEALS:2015-09-25
Date Deposited:2000


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