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Title:Probing the Roles of Metal Binding Ligands in Cupredoxins: Incorporating Nonproteinogenic Amino Acids Into Azurin and Copper a Azurin
Author(s):Clark, Kevin M.
Doctoral Committee Chair(s):Lu, Yi; Wilfred Van Der Donk
Department / Program:Biochemistry
Discipline:Biochemistry
Degree Granting Institution:University of Illinois at Urbana-Champaign
Degree:Ph.D.
Genre:Dissertation
Subject(s):Chemistry, Biochemistry
Abstract:In summary, a means to investigate the specific function of individual metal ligand residues in azurin and CuA azurin by using EPL to incorporate nonproteinogenic amino acid analogues has been demonstrated. This work has resulted in new insights into the role of the metal ligands and has shaped future metalloprotein engineering efforts.
Issue Date:2010
Type:Text
Language:English
Description:217 p.
Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 2010.
URI:http://hdl.handle.net/2142/84870
Other Identifier(s):(MiAaPQ)AAI3452158
Date Available in IDEALS:2015-09-25
Date Deposited:2010


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