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Title:Characterization of the Yeast Gpi3 Protein, the Catalytic Subunit of the First Enzyme Complex in GPI Anchor Biosynthesis
Author(s):Kostova, Zlatka
Doctoral Committee Chair(s):Peter A.B.Orlean
Department / Program:Biochemistry
Discipline:Biochemistry
Degree Granting Institution:University of Illinois at Urbana-Champaign
Degree:Ph.D.
Genre:Dissertation
Subject(s):Biology, Molecular
Abstract:I also undertook to disrupt the S. pombe gpi3 + gene and to carry out comparative studies of the fungal and human Gpi3p homologs. The S. pombe gpi3+ gene was found to be essential for cell viability in this organism. The in vivo complementation studies indicated that the S. pombe, S. cerevisiae, and H. sapiens enzymes, although very similar at the amino acid level, do not complement each other.
Issue Date:1999
Type:Text
Language:English
Description:211 p.
Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 1999.
URI:http://hdl.handle.net/2142/84909
Other Identifier(s):(MiAaPQ)AAI9953066
Date Available in IDEALS:2015-09-25
Date Deposited:1999


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