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Title:Yeast Mutants That Require the GPI Biosynthetic Gene GPI1 for Growth
Author(s):Taron, Barbara Westfall
Doctoral Committee Chair(s):Peter A.B.Orlean
Department / Program:Biochemistry
Discipline:Biochemistry
Degree Granting Institution:University of Illinois at Urbana-Champaign
Degree:Ph.D.
Genre:Dissertation
Subject(s):Biology, Molecular
Abstract:The isolation of t-s smp3, gaa1, and gpi2 strains using a synthetic lethality screen demonstrates that this is a valid approach to identify genes involved in GPI anchor biosynthesis. This suggests that many of the remaining S.L. mutants are also likely to harbor mutations in GPI and cell wall assembly. Strategies to identify the remaining non- t-s/S.L. mutations include complementation of other conditional growth phenotypes (e.g. CFW hypersensitivity) or the non-sectoring phenotype.
Issue Date:2000
Type:Text
Language:English
Description:155 p.
Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 2000.
URI:http://hdl.handle.net/2142/84920
Other Identifier(s):(MiAaPQ)AAI9990161
Date Available in IDEALS:2015-09-25
Date Deposited:2000


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