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Description
Title: | Yeast Mutants That Require the GPI Biosynthetic Gene GPI1 for Growth |
Author(s): | Taron, Barbara Westfall |
Doctoral Committee Chair(s): | Peter A.B.Orlean |
Department / Program: | Biochemistry |
Discipline: | Biochemistry |
Degree Granting Institution: | University of Illinois at Urbana-Champaign |
Degree: | Ph.D. |
Genre: | Dissertation |
Subject(s): | Biology, Molecular |
Abstract: | The isolation of t-s smp3, gaa1, and gpi2 strains using a synthetic lethality screen demonstrates that this is a valid approach to identify genes involved in GPI anchor biosynthesis. This suggests that many of the remaining S.L. mutants are also likely to harbor mutations in GPI and cell wall assembly. Strategies to identify the remaining non- t-s/S.L. mutations include complementation of other conditional growth phenotypes (e.g. CFW hypersensitivity) or the non-sectoring phenotype. |
Issue Date: | 2000 |
Type: | Text |
Language: | English |
Description: | 155 p. Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 2000. |
URI: | http://hdl.handle.net/2142/84920 |
Other Identifier(s): | (MiAaPQ)AAI9990161 |
Date Available in IDEALS: | 2015-09-25 |
Date Deposited: | 2000 |
This item appears in the following Collection(s)
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Dissertations and Theses - Biochemistry
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Graduate Dissertations and Theses at Illinois
Graduate Theses and Dissertations at Illinois