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Title:Metabolic Responses During Recovery From Prolonged Exercise: Role of Nutrition and Hormones
Author(s):Gautsch, Tracy Anne
Doctoral Committee Chair(s):Layman, Donald K.
Department / Program:Nutritional Sciences
Discipline:Nutritional Sciences
Degree Granting Institution:University of Illinois at Urbana-Champaign
Subject(s):Health Sciences, Rehabilitation and Therapy
Abstract:The second specific aim of this research was to investigate the regulation of insulin-like growth factor binding protein-1 production following exercise. Prolonged exercise increased plasma and hepatic levels of IGFBP-1. Neither plasma insulin and glucose levels, nor meal composition altered IGFBP-1 production following exercise. Conversely, adaptation to treadmill running markedly suppressed IGFBP-1 production, suggesting a connection between exercise stress and IGFBP-1. Further, plasma corticosterone correlated to plasma IGFBP-1 in untrained and treadmill-adapted animals following exercise. However, pre-treatment with drugs that block corticosterone synthesis and bioactivity did not prevent IGFBP-1 from rising following exercise. These results demonstrate that upregulation of IGFBP-1 following exercise is corticosteroid-independent. Further research is needed to determine the chemical factor(s) inducing IGFBP-1 production following exercise.
Issue Date:1998
Description:161 p.
Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 1998.
Other Identifier(s):(MiAaPQ)AAI9904462
Date Available in IDEALS:2015-09-25
Date Deposited:1998

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