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Title:The Effect of Ethanol and Acetaldehyde on Formation and Repair of Carcinogen-Dna Adducts in the Mammary Gland
Author(s):Barnes, Sean Lenard
Doctoral Committee Chair(s):Singletary, Keith W.
Department / Program:Nutritional Sciences
Discipline:Nutritional Sciences
Degree Granting Institution:University of Illinois at Urbana-Champaign
Degree:Ph.D.
Genre:Dissertation
Subject(s):Health Sciences, Toxicology
Abstract:In conclusion, both ethanol and acetaldehyde are capable of enhancing carcinogen-DNA adduct formation and inhibiting removal. However, these effects are dependent on the concentrations of ethanol or acetaldehyde, the time of exposure and the dose of carcinogen. Additionally, these effects, particularly those related to adduct formation, may be explained by either decreases in levels of carcinogen-detoxifying enzymes or an overall increase in oxidative stress.
Issue Date:1999
Type:Text
Language:English
Description:134 p.
Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 1999.
URI:http://hdl.handle.net/2142/84983
Other Identifier(s):(MiAaPQ)AAI9944791
Date Available in IDEALS:2015-09-25
Date Deposited:1999


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