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Title:Evaluation of Metabolic Endpoints for Use as Biomarkers of Exposure to Environmental Estrogens and in Bioassays of Their Activity
Author(s):Dean-Colomb, Windy Marie
Doctoral Committee Chair(s):Jeffery, Elizabeth H.
Department / Program:Biology
Discipline:Biology
Degree Granting Institution:University of Illinois at Urbana-Champaign
Degree:Ph.D.
Genre:Dissertation
Subject(s):Environmental Sciences
Abstract:These findings indicate that angiotensinogen and uterine complement C3 can serve as sensitive indicators of estrogenicity. Additionally, angiotensinogen has the potential to be a biomarker of exposure to estrogenic compounds because its measurement only requires a blood sample, while providing a sensitive biochemical endpoint to supplement the uterotrophic assay. Nevertheless, other endpoints that can be used as potential biomarkers of environmental estrogen exposure are still needed since angiotensinogen is not specific to estrogens and thus cannot be used alone.
Issue Date:2004
Type:Text
Language:English
Description:180 p.
Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 2004.
URI:http://hdl.handle.net/2142/85351
Other Identifier(s):(MiAaPQ)AAI3130907
Date Available in IDEALS:2015-09-25
Date Deposited:2004


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