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Title:Characterization and Efficacy of Cobalt Compounds as in Vivo Magnetic Resonance Temperature Probes
Author(s):Wilmes, Lisa Jeanne
Doctoral Committee Chair(s):Richard L. Magin
Department / Program:Biophysics
Discipline:Biophysics
Degree Granting Institution:University of Illinois at Urbana-Champaign
Degree:Ph.D.
Genre:Dissertation
Subject(s):Biophysics, General
Abstract:This work demonstrates that $\sp{59}$Co NMR can be used to determine temperature changes in vivo. The liposome encapsulated $\rm \lbrack Co(en)\sb3\rbrack Cl\sb3$ and Co(Hp) (Im) $\sb2\sp+$ show promise as in vivo MR temperature probes. The relatively high accumulation of Co(Hp) (Im) $\sb2\sp+$ in tumors indicates that this configuration may have potential for measuring tumor temperature during hyperthermic treatment of cancer.
Issue Date:1998
Type:Text
Language:English
Description:140 p.
Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 1998.
URI:http://hdl.handle.net/2142/85485
Other Identifier(s):(MiAaPQ)AAI9904623
Date Available in IDEALS:2015-09-25
Date Deposited:1998


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