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Title:Vascular and Neuro-Inflammatory Modulation Following Resistance Training in Young African American and White Men
Author(s):Heffernan, Kevin Scott
Doctoral Committee Chair(s):Fernhall, Bo
Department / Program:Kinesiology and Community Health
Discipline:Kinesiology and Community Health
Degree Granting Institution:University of Illinois at Urbana-Champaign
Degree:Ph.D.
Genre:Dissertation
Subject(s):Black Studies
Abstract:African American men have a higher incidence of hypertension and associated co-morbidities. Altered vascular and autonomic function has been implicated in the pathogenesis of cardiovascular diseases in this population. We sought to examine the effect of resistance exercise training on vascular and autonomic function in young African American and white men. Several non-invasive methods were used to assess macrovascular structure, macrovascular/microvascular function, limb blood blow, central and peripheral blood pressure, and cardiac autonomic modulation. Multiple methodologies were employed in order to provide a comprehensive examination of vascular and autonomic physiology. Resistance training improved vagal tone, reduced C-reactive protein, reduced central (i.e. aortic and carotid) blood pressure and improved microvacular endothelial function in both African American and white men. Resistance training had no effect on arterial stiffness or wave reflection. This occurred with no change in brachial blood pressure, body fat, cardiorespiratory fitness, blood lipid levels or fasting glucose. In conclusion, resistance training improves vascular and autonomic function while reducing inflammation in African American men. Thus, this exercise modality may be a useful lifestyle intervention for abrogating cardiovascular risk in this high-risk population.
Issue Date:2008
Type:Text
Language:English
Description:129 p.
Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 2008.
URI:http://hdl.handle.net/2142/86401
Other Identifier(s):(MiAaPQ)AAI3337787
Date Available in IDEALS:2015-09-28
Date Deposited:2008


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