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Title:DNA -Protein Interactions in the CTnDOT Excisive Intasome
Author(s):Dichiara, Jeanne M.
Doctoral Committee Chair(s):Gardner, Jeffrey F.
Department / Program:Microbiology
Discipline:Microbiology
Degree Granting Institution:University of Illinois at Urbana-Champaign
Degree:Ph.D.
Genre:Dissertation
Subject(s):Biology, Microbiology
Abstract:The excision mechanism of CTnDOT is more complicated than any system studied to date. Excision requires multiple accessory proteins. Exc is one protein required for excision, however, its function is unknown. In an attempt to determine a role for Exc, the native wild type Exc protein was purified. These studies indicated that Exc might interact with IntDOT during excision, as determined by electrophoretic mobility shift assays. Further studies of Exc are warranted to answer the many questions that still remain about its function.
Issue Date:2006
Type:Text
Language:English
Description:155 p.
Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 2006.
URI:http://hdl.handle.net/2142/86685
Other Identifier(s):(MiAaPQ)AAI3242833
Date Available in IDEALS:2015-09-28
Date Deposited:2006


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