Acute Effects of Episodic PCB Congeners on the Hypothalamo -Pituitary-Thyroid (Hpt) Axis in Weanling Female Rats

Khan, Moazzam Ali

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Title:	Acute Effects of Episodic PCB Congeners on the Hypothalamo -Pituitary-Thyroid (Hpt) Axis in Weanling Female Rats
Author(s):	Khan, Moazzam Ali
Doctoral Committee Chair(s):	Hansen, Larry G.
Department / Program:	Veterinary Clinical Medicine
Discipline:	Veterinary Clinical Medicine
Degree Granting Institution:	University of Illinois at Urbana-Champaign
Degree:	Ph.D.
Genre:	Dissertation
Subject(s):	Biology, Veterinary Science
Abstract:	These studies demonstrate that brief exposure to ortho-substituted PCBs can cause alterations in the HPT axis in immature animals. The data indicate that ortho-PCBs 95 or 101 cause secondary or pituitary-related hypothyroidism. There is also evidence that these PCBs may be affecting the HPT-axis through multiple mechanisms.
Issue Date:	2001
Type:	Text
Language:	English
Description:	157 p. Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 2001.
URI:	http://hdl.handle.net/2142/87112
Other Identifier(s):	(MiAaPQ)AAI3030445
Date Available in IDEALS:	2015-09-28
Date Deposited:	2001