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Title:Antifreeze Glycoproteins of Two Unrelated Polar Fishes: Gene Structure, Organization and Evolution
Author(s):Chen, Liangbiao
Doctoral Committee Chair(s):DeVries, Arthur L.
Department / Program:Molecular and Integrative Physiology
Discipline:Molecular and Integrative Physiology
Degree Granting Institution:University of Illinois at Urbana-Champaign
Degree:Ph.D.
Genre:Dissertation
Subject(s):Biology, Genetics
Abstract:The AFGPs of the northern cods are also encoded by a family of polyprotein genes in which multiple AFGP coding sequences linked in tandem by small cleavable spacers Args or Arg-Ala-Ala-Arg's. However, the northern cod AFGP genes show no sequence identity with trypsinogen gene, indicating trypsinogen gene is not the progenitor of this group of AFGP genes. The southern and northern AFGP genes also have different signal peptides, different intron-exon organizations, different spacer sequences thus are the processing of the polyprotein precursors, and drastically different codon patterns for the repetitive AFGP coding sequence. This molecular evidence in conjunction with paleontological and paleoclimatic data indicate the near-identical AFGPs of Antarctic notothenioids and northern cods evolved independently.
Issue Date:1997
Type:Text
Language:English
Description:187 p.
Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 1997.
URI:http://hdl.handle.net/2142/87256
Other Identifier(s):(MiAaPQ)AAI9717261
Date Available in IDEALS:2015-09-28
Date Deposited:1997


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