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Title:Diffusion and Magnetization Transfer Studies of Neural Tissue
Author(s):Gulani, Vikas
Doctoral Committee Chair(s):Lauterbur, Paul C.
Department / Program:Physiology
Discipline:Physiology
Degree Granting Institution:University of Illinois at Urbana-Champaign
Degree:Ph.D.
Genre:Dissertation
Subject(s):Biology, Animal Physiology
Abstract:Our experiments showed that diffusion and magnetization transfer do not offer a unique window to neural function, as had been suggested by some reports in the literature. Rather, our studies taken together with the literature suggest that both these phenomena affect the standard hemodynamics-dependent functional MRI signal. The work presented here therefore helps to understand previously reported observations about diffusion and magnetization transfer. En route to testing the possibility of using diffusion imaging to image neural function, a new apparent diffusion tensor (ADT) imaging pulse sequence was developed and tested, and better insight into the measurement of the ADT was reached using both experiments and simulations.
Issue Date:1998
Type:Text
Language:English
Description:136 p.
Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 1998.
URI:http://hdl.handle.net/2142/87266
Other Identifier(s):(MiAaPQ)AAI9912248
Date Available in IDEALS:2015-09-28
Date Deposited:1998


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