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application/vnd.openxmlformats-officedocument.presentationml.presentation ![]() | Presentation | Microsoft PowerPoint 2007 |
application/pdf ![]() | Abstract |
Description
Title: | Structural expression of exo-anomeric effect |
Author(s): | Alonso, E.R. |
Contributor(s): | Alonso, José L.; Cabezas, Carlos; Peña, Isabel |
Subject(s): | Structure determination |
Abstract: | Structural signatures for exo--anomeric effect have been extracted from the archetypal methyl--$\beta$--D--xyloside using broadband Fourier transform microwave spectroscopy combined with laser ablation. Spectrum analysis allows the determination of a set of rotational constants, which has been unequivocally attributed to conformer cc--$\beta$-$^{4}$C$_{1}$ g-, corresponding to the global minimum of the potential energy surface, where the aglycon residue (CH$_{3}$) orientation contributes towards maximization of the exo-anomeric effect. Further analysis allowed the determination of the r$_{s}$ structure, based on the detection of eleven isotopologues - derived from the presence of six $^{13}$C and five $^{18}$O atoms - observed in their natural abundances. The observed glycosidic C$_{1}$-O$_{1}$ bond length decrease (1.38 \AA) can be interpreted in terms of the exo--anomeric effect. As such, the exo--anomeric effect presents itself as one of the main driving forces controlling the shape of many biologically important oligosaccharides. |
Issue Date: | 2016-06-20 |
Publisher: | International Symposium on Molecular Spectroscopy |
Genre: | Conference Paper / Presentation |
Type: | Text |
Language: | En |
URI: | http://hdl.handle.net/2142/91335 |
Rights Information: | Copyright 2016 by the authors |
Date Available in IDEALS: | 2017-01-26 |