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Title:Brain anatomy: investigations of the effects of aging, fitness, and arterial stiffness
Author(s):Fletcher, Mark Allen
Director of Research:Fabiani, Monica; Gratton, Gabriele
Doctoral Committee Chair(s):Fabiani, Monica; Gratton, Gabriele
Doctoral Committee Member(s):Sutton, Brad; Dye, Matthew
Department / Program:Neuroscience Program
Discipline:Neuroscience
Degree Granting Institution:University of Illinois at Urbana-Champaign
Degree:Ph.D.
Genre:Dissertation
Subject(s):Neuroscience
Anatomy
Aging
Cerebrovascular
Fletcher
Fitness
Abstract:This work explores the mechanisms and lifestyle modifiers of brain anatomy throughout the aging process. First, a thorough review of the mechanisms of fitness on brain anatomy is presented. Next, a study examining the effects of aging and fitness on cortical and subcortical brain anatomy in a group of older adults (55-87 years old) is presented. We examine the degree to which cortical, subcortical, and global volumes are sensitive to both age and fitness. Lastly, the effect of cerebrovascular stiffness on the anatomical difference between and within individual subjects is explored across the lifespan (18-75 years old).
Issue Date:2017-05-19
Type:Thesis
URI:http://hdl.handle.net/2142/98210
Rights Information:Copyright 2017 Mark Allen Fletcher
Date Available in IDEALS:2017-09-29
Date Deposited:2017-08


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