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Title:Sex differences on the effect of obesity on the morphology of the intestinal epithelium
Author(s):Mei, Angelina; Zhou, Weinan; Davis, Elizabeth A.; Dailey, Megan J.
sex differences
Abstract:It is known that obesity causes the morphology of lining of the small intestine, the epithelium, to change. It causes the villi, the finger like projections responsible for nutrient absorption, to be longer. It also causes the crypts, which contain the stem cells, to be deeper. The differences of morphology between male and female mice have not been previously studied. This project involves inducing obesity in mice using a high fat diet and then observing the effect on the length of the villi and crypts of in the small intestine. Results from this study can contribute to the understanding of the mechanisms of nutrient triggered cellular adaption of the intestine and can also provide insight to intestinal diseases.
Issue Date:2018-04
Genre:Conference Poster
Rights Information:Copyright 2018 Angelina Mei
Copyright 2018 Weinan Zhou
Copyright 2018 Elizabeth A. Davis
Copyright 2018 Megan J. Dailey
Date Available in IDEALS:2018-04-23

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