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text Mateus-Pinilla, Nohra Dorak, Sheena Jean 2018-08-14T21:37:11Z 2018-08-14T21:37:11Z 2020-08-15T09:15:08Z 2016-12-06 2016-12 Soil is an important reservoir for chronic wasting disease (CWD) which is a prion disease that infects cervids through both direct contact with infected animals and contact with contaminated environments. I built a boosted regression tree model that accurately predicted (AUC = 0.954) the probability of CWD presence in northern Illinois based on soil characteristics (soil texture, pH, cation exchange capacity, organic matter, and water content), then used the outcome to assess possible pathways by which soil characteristics increase the probability of transmission via environmental contamination. The model indicates CWD is likely to be present where: soil pH is greater than 6.6, percent clay is lower than 20%, cation exchange capacity (CEC) is lower than 15 meq/100g, and soil organic matter is less than 4.5%. Soil pH and the abundance of clays and associated soil organic matter and CEC appear to alter the availability of prions immobilized in soil. The results suggest that exposure to prions through probable routes of infection such as inhalation or ingestion is greatest where pH is greater than 6.6 and the percent clay is less than 20%. Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2018-12-01 The student, Sheena Dorak, accepted the attached license on 2016-12-06 at 09:48. The student, Sheena Dorak, submitted this Thesis for approval on 2016-12-06 at 09:59. This Thesis was approved for publication on 2016-12-06 at 14:21. DSpace SAF Submission Ingestion Package generated from Vireo submission #10445 on 2018-08-14 at 16:00:19 Made available in DSpace on 2018-08-14T21:37:11Z (GMT). No. of bitstreams: 3 DORAK-THESIS-2016.pdf: 814346 bytes, checksum: 314c19180776c456b8bffc628ec3a9f2 (MD5) SJDorak MS Thesis.docx: 846906 bytes, checksum: bc5e601d7f122e434401b9b90e57fb42 (MD5) LICENSE.txt: 4209 bytes, checksum: e5a2292295513fc24b1d7fb89e4ec8c4 (MD5) Previous issue date: 2016-12-06 Embargo set by: Seth Robbins for item 106496 Lift date: 2020-08-14T21:37:20Z Reason: Author requested closed access (OA after 2yrs) in Vireo ETD system Limited Restriction Lifted for Item 106496 on 2020-08-15T09:15:08Z. application/pdf http://hdl.handle.net/2142/100416 en Copyright 2016 Sheena Dorak Chronic wasting disease soil Soil PH and clay content associated with chronic wasting disease in white-tailed deer in northern Illinois text Natural Res & Env Sci Natural Res & Env Sciences University of Illinois at Urbana-Champaign Thesis M.S.