2026-09-23T00:40:55Z https://www.ideals.illinois.edu/oai-pmh

oai:www.ideals.illinois.edu:2142/115887 2023-07-11 col_2142_5131 col_2142_11615 com_2142_5130 com_2142_9130 com_2142_8903

Kong, Hyunjoon Kong, Hyunjoon Boppart, Stephen A Flaherty, David W Kraft, Mary L 2022-08 application/pdf en text Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2024-08-01 The student, Yu-Heng Deng, accepted the attached license on 2022-07-05 at 10:16. The student, Yu-Heng Deng, submitted this Dissertation for approval on 2022-07-05 at 10:25. This Dissertation was approved for publication on 2022-07-06 at 16:44. DSpace SAF Submission Ingestion Package generated from Vireo submission #18141 on 2022-11-16 at 10:17:40 Active matter for removal of biofilm and endocrine-disrupting chemicals Deng, Yu-Heng 2022-07-06 Biofilm BPA Biofilm and endocrine-disrupting chemicals are critical environmental problems that impact human’s health. Although a number of strategies have been proposed to address these issues, the recurrence of biofilm and endocrine-disrupting chemicals in the environment keep exerting adverse effects on our daily lives. To this end, the overall goal of my research is to develop a system of active matter for the removal of biofilm and endocrine-disrupting chemicals. In this dissertation, Chapter 1 discusses the methodologies of active matter fabrication, the fundamental issues caused by biofilm and endocrine-disrupt chemicals, and the current constraints in the removal of these two issues. Chapter 2 presents the design of active matter, so-called self- locomotive, antimicrobial microrobot (SLAM), and explains its mechanism to eliminate biofilm from target bio-fouled structures. Based on the findings in Chapter 2, Chapter 3 investigates how to prevent biofilm recurrence by constructing a collective analysis to understand the biofilm composition. Chapter 4 further explores how SLAM can be applied as a micro-cleaner to remove endocrine-disrupting chemicals through its intrinsic oxidation capability, along with in vitro studies that examines the toxicity of endocrine-disrupting chemicals after the treatments. Lastly, Chapter 5 summarizes the key findings through Chapter 2 to Chapter 4 and proposes the directions for future investigations. Thesis eng https://hdl.handle.net/2142/115887 Copyright 2022 Yu-Heng Deng Ph.D. Dissertation Chemical Engineering University of Illinois at Urbana-Champaign Chemical & Biomolecular Engr