2026-09-20T20:28:01Z https://www.ideals.illinois.edu/oai-pmh

oai:www.ideals.illinois.edu:2142/16225 2023-07-10 col_2142_5131 col_2142_14787 com_2142_5130 com_2142_9630 com_2142_234

Georgiadis, John G. Johnson, Curtis L. 2010-05-19T18:41:09Z 2010-05-19T18:41:09Z 2010-05-19T18:41:09Z This thesis aims to investigate vibrational characteristics of magnetic resonance elastography (MRE) of the brain. MRE is a promising, non-invasive methodology for the mapping of shear stiffness of the brain. A mechanical actuator shakes the brain and generates shear waves, which are then imaged with a special MRI sequence sensitive to sub-millimeter displacements. This research focuses on exploring the profile of vibrations utilized in brain elastography from the standpoint of ultimately investigating nonlinear behavior of the tissue. The first objective seeks to demonstrate the effects of encoding off-frequency vibrations using standard MRE methodologies. Vibrations of this nature can arise from nonlinearities in the system and contaminate the results of the measurement. The second objective is to probe nonlinearity in the dynamic brain system using MRE. A non-parametric decomposition technique, novel to the MRE field, is introduced and investigated. Item withdrawn by Mark Zulauf (zulauf@illinois.edu) on 2010-04-29T14:07:12Z Item was in collections: University of Illinois Theses & Dissertations (ID: 1) No. of bitstreams: 1 Johnson_Curtis.pdf: 1692448 bytes, checksum: 5095215c8e9412caaf7bf9f597b61287 (MD5) Made available in DSpace on 2010-05-19T18:41:09Z (GMT). No. of bitstreams: 2 Johnson_Curtis.pdf: 1692448 bytes, checksum: 5095215c8e9412caaf7bf9f597b61287 (MD5) license.txt: 4064 bytes, checksum: 4c48faf59a459d77380005e9de0d3b3e (MD5) http://hdl.handle.net/2142/16225 en Copyright 2010 Curtis L. Johnson Magnetic resonance imaging Magnetic resonance elastography Tissue stiffness Brain Vibrational characteristics of brain magnetic resonance elastography 2010-5 Mechanical Sci & Engineering 1917 Mechanical Engineering 0133 University of Illinois at Urbana-Champaign Thesis M.S. MS:Mechanical Engineerng -UIUC 10KS0133MS