2026-09-20T15:54:29Z https://www.ideals.illinois.edu/oai-pmh

oai:www.ideals.illinois.edu:2142/16720 2023-07-10 col_2142_5131 col_2142_10761 com_2142_5130 com_2142_10755 com_2142_234

Belford, Geneva Belford, Geneva G. Kelleher, Neil L. Han, Jiawei Zhai, ChengXiang Kim, Yong-Bin 2010-08-20T17:55:52Z 2010-08-20T17:55:52Z 2010-08-20T17:55:52Z 2010-08 Top-down proteomics is a revolutionary application for the identification and characterization of protein, known to be one of the most complicated and challenging issues in biology. In top-down proteomics, the quality and speed of the data warehouse is very important, as high accuracy results are returned by a database search. ProSight Warehouse fills the critical role as the data warehouse for ProSight PTM, the first publicly available top-down proteomics software suite. MySQL, a free relational database, was the base of this warehouse. Many annotated and predicted protein forms have been successfully incorporated into the organism-specific database and in the integrated database for human strains. To achieve high quality and efficiency, a database schema (Absolute Mass Search), data annotation methods (Shotgun and Extended Shotgun Annotation), data population strategies (on-the-fly population, bulk-loading method), and a database integration methodology for human protein were developed. With the successful implementation of ProSight Warehouse, ProSight PTM achieved its aspiration, highly accurate protein identification and characterization. Item withdrawn by Mark Zulauf (zulauf@illinois.edu) on 2010-07-12T20:45:20Z Item was in collections: University of Illinois Theses & Dissertations (ID: 1) No. of bitstreams: 1 Kim_Yong-Bin.pdf: 3028764 bytes, checksum: 357c9d473a8aee82ad6792d262611222 (MD5) Made available in DSpace on 2010-08-20T17:55:52Z (GMT). No. of bitstreams: 3 Kim_Yong-Bin.pdf: 3028764 bytes, checksum: 357c9d473a8aee82ad6792d262611222 (MD5) 1_Kim_Yong-Bin.pdf: 3028771 bytes, checksum: 2c456fde326686e4e86b12a5c74d2cd8 (MD5) license.txt: 4055 bytes, checksum: f0093863896a06144826951bcbf44042 (MD5) http://hdl.handle.net/2142/16720 en Copyright 2010 Yong-Bin Kim Top-down proteomics Database support for proteomics Prosight PTM Prosight Warehouse Biological warehouse integration Data warehouse Database support for top-down proteomics Computer Science 1434 Computer Science 0112 University of Illinois at Urbana-Champaign Dissertation Ph.D. PHD:Computer Science -UIUC 10KS0112PHD