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oai:www.ideals.illinois.edu:2142/18621 2023-07-10 col_2142_5131 col_2142_14837 com_2142_5130 com_2142_14836 com_2142_234

Boppart, Stephen A. Li, Di 2011-01-21T22:52:04Z 2011-01-21T22:52:04Z 2013-01-22T11:00:16Z 2011-01-21T22:52:04Z 2010-12 In this thesis, a catheter design is proposed for endoscopic magnetomotive optical coherence tomography (MM-OCT). Magnetomotive optical coherence tomography is a novel technique which uses targeted magnetic contrast agents for contrast enhancement of OCT imaging. In MM-OCT, microspheres and magnetic nanoparticles (MNPs) are introduced into tissue and an electromagnet is used to generate a small modulated magnetic field within the tissue during OCT imaging. The magnetic field will introduce mechanical displacement of the MNPs, which can be detected, and the MM-OCT signal can be measured. The current bench-top set-up does not allow for in vivo MM-OCT imaging because the magnetic field is provide by a solenoid with an outer diameter of ~18 mm and an axial thickness of ~9 mm. A magnetomotive catheter design was developed by wrapping small coil around the distal end of a standard OCT catheter to combine the novel MM-OCT technology and catheter-based OCT. The coil has a small size while providing a local magnetic field for MM-OCT imaging. This magnetomotive catheter will enable investigations of in vivo magnetomotive contrast enhancement from the magnetic agents used in MM-OCT imaging. Item withdrawn by Mark Zulauf (zulauf@illinois.edu) on 2010-12-07T16:49:03Z Item was in collections: University of Illinois Theses & Dissertations (ID: 1) No. of bitstreams: 1 Li_Di.pdf: 1921089 bytes, checksum: a7779306be7916ab6b2ce0a657966dbb (MD5) Made available in DSpace on 2011-01-21T22:52:04Z (GMT). No. of bitstreams: 2 Li_Di.pdf: 1920983 bytes, checksum: 37e3ebc244e74bd97abfc30a5c2b1787 (MD5) license.txt: 4052 bytes, checksum: 73931c2df370ba31223e28669d711400 (MD5) Item marked as restricted to the 'Administrator' Group (id=1) by William Ingram (wingram2@illinois.edu) on 2011-01-21T22:53:55Z Item is restricted until 2013-01-21T22:53:34Z Item reinstated by Sarah Shreeves (sshreeve@illinois.edu) on 2013-01-22T11:00:16Z Item was in collections: University of Illinois Dissertations and Theses (ID: 204) Dissertations and Theses - Nuclear, Plasma, and Radiological Engineering (ID: 693) No. of bitstreams: 3 Li_Di.pdf.txt: 81500 bytes, checksum: b2fd90565f289598f4cb58847f28e543 (MD5) Li_Di.pdf: 1920983 bytes, checksum: 37e3ebc244e74bd97abfc30a5c2b1787 (MD5) license.txt: 4052 bytes, checksum: 73931c2df370ba31223e28669d711400 (MD5) Item released from any restrictions by Sarah Shreeves (sshreeve@illinois.edu) on 2013-01-22T11:00:16Z http://hdl.handle.net/2142/18621 en Copyright 2010 Di Li Optical Coherence Tomography Catheter Magnetomotive optical coherence tomography (OCT) Catheter for endoscopic magnetomotive optical coherence tomography Nuclear, Plasma, & Rad Engr 1973 Nuclear Engineering 0139 University of Illinois at Urbana-Champaign Thesis M.S. PHD:Nuclear Engineering -UIUC 10KS0139PHD