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Forsyth-Whalen, Elizabeth 2011-05-07T12:17:50Z 2011-05-07T12:17:50Z 10000-01-01 1993 Elevated lipoprotein (a) concentration (Lp(a)) ($>$30 mg/dl particle mass) is an independent risk factor for coronary artery disease (CAD). It has been suggested that intense exercise lowers plasma (Lp(a)) in healthy individuals. To study the efficacy of moderate intensity exercise in lowering (Lp(a)), 11 men (M age = 60) and 5 women (M age = 70) with angiographically documented CAD participated in an 8-week Phase II cardiac rehabilitation program (30 minutes of treadmill, bicycle, wall-pulley, rowing machine or arm ergometer) three times a week. Subjects began at an intensity of 2.5 $\pm$ 0.5 METS and attended a minimum of 75% of all exercise sessions (M = 88%). A subgroup of 4 men and 1 woman with angiographically documented CAD who refused the exercise program but underwent identical testing was compared. Plasma (Lp(a)) was determined by immunoprecipitation analysis at the beginning and end of the 8-week exercise period. Subjects kept 3-day diet and physical activity diaries and had body composition measurements (weight, percent body fat and waist to hip ratio (WHR)) taken at the beginning and end of the 8-week testing period. Although subjects with higher initial plasma (Lp(a)) showed greater decreases in (Lp(a)), a t-test revealed no change (p = 0.26) in plasma (Lp(a)) in the exercising subjects over the 8-week period. Absolute changes in plasma (Lp(a)) did not correlate with absolute changes in weight or percent body fat. Women had significantly higher (p $\le$ 0.05) pretest plasma (Lp(a)) than men although changes in plasma (Lp(a)) were not different between sexes. The results suggest that an 8-week exercise program of moderate intensity does not assure favorable changes in plasma (Lp(a)). Made available in DSpace on 2011-05-07T12:17:50Z (GMT). No. of bitstreams: 2 license.txt: 4922 bytes, checksum: 910b249b4beec47e7ab768910c8f966f (MD5) 9411624.pdf: 4451546 bytes, checksum: 47f5dc93c31b4a5ca4efa9f25be9a14f (MD5) Previous issue date: 1993 Item marked as restricted to the 'UIUC Users [automated]' Group (id=2) by Howard Ding (hding2@illinois.edu) on 2011-05-07T14:39:17Z Item is restricted indefinitely. Restriction data tranferred 2014-07-01T11:16:30-05:00 Original Data Group with Access UIUC Users [automated] Release Date: none Reason: ETDs are only available to UIUC Users without author permission ETDs are only available to UIUC Users without author permission U of I Only AAI9411624 (UMI)AAI9411624 http://hdl.handle.net/2142/19765 eng Copyright 1993 Forsyth-Whalen, Elizabeth Biology, General Health Sciences, General Health Sciences, Recreation The effects of an eight week cardiac rehabilitation exercise program on Lp(a) concentration in patients with coronary artery disease text Kinesiology and Community Health Kinesiology University of Illinois at Urbana-Champaign Dissertation Ph.D.