2026-09-20T20:25:17Z https://www.ideals.illinois.edu/oai-pmh

oai:www.ideals.illinois.edu:2142/26150 2023-07-10 col_2142_5131 col_2142_8888 com_2142_5130 com_2142_8887 com_2142_234

Cunningham, Brian T. Chu, Allen C. 2011-08-25T22:16:22Z 2011-08-25T22:16:22Z 2011-08-25T22:16:22Z 2011-08 The development of the instrumentation behind a biosensor system based on a vertically emitting distributed feedback laser is presented. The performance of the label-free high-resolution biomolecular detection system is optimized for use in applications that require the study of large quantities of parallel interactions that could be adversely affected by the use of molecular labels, such as high-throughput pharmaceutical drug screenings. A series of filtering and averaging methods for minimizing the effects of sensor noise are discussed in the analysis of both single spectrum measurements and kinetic scans over time. An example biochemical assay is performed to demonstrate and evaluate the current capabilities of the biosensor system. Plans for the future advancement of the system, including the possibilities of hardware improvements, device fabrication refinements, data analysis enhancements, and new usage models, are considered. Item withdrawn by Mark Zulauf (zulauf@illinois.edu) on 2011-07-04T17:26:19Z Item was in collections: University of Illinois Theses & Dissertations (ID: 1) No. of bitstreams: 2 Chu_Allen.docx: 3086610 bytes, checksum: d99bdafd3189c92cc81a81dd1fe42288 (MD5) Chu_Allen.pdf: 4136153 bytes, checksum: 9ea57405b7f9ec44681327355ed451b3 (MD5) Made available in DSpace on 2011-08-25T22:16:22Z (GMT). No. of bitstreams: 3 Chu_Allen.pdf: 4136153 bytes, checksum: 9ea57405b7f9ec44681327355ed451b3 (MD5) license.txt: 4056 bytes, checksum: 702db5ecc5b710993a98514ac5489614 (MD5) Chu_Allen.docx: 3086610 bytes, checksum: d99bdafd3189c92cc81a81dd1fe42288 (MD5) http://hdl.handle.net/2142/26150 en Copyright 2011 Allen C. Chu Distributed Feedback Laser Biosensor Instrumentation Biochemical Assay Label Free Biomolecular Detection Small Molecule Interaction Instrumentation for a distributed feedback laser biosensor system Electrical & Computer Eng 1933 Electrical & Computer Engr 1200 University of Illinois at Urbana-Champaign Thesis M.S. MS:Electr & Computer Eng-UIUC 10KS1200MS