2026-09-21T10:00:43Z https://www.ideals.illinois.edu/oai-pmh

oai:www.ideals.illinois.edu:2142/34215 2023-07-10 col_2142_5131 col_2142_8888 com_2142_5130 com_2142_8887 com_2142_234

Boppart, Stephen A. Boppart, Stephen A. Blahut, Richard E. Allen, Jont B. Novak, Michael A. Nguyen, Cac 2012-09-18T21:06:13Z 2012-09-18T21:06:13Z 2012-08 2012-09-18T21:06:13Z 2012-08 Otitis media (OM) is a middle ear infection caused by bacterial growth between the tympanic membrane (TM) and the inner ear. Children with chronic OM, including OM with effusion and recurrent OM, often have conductive hearing loss and communication difficulties, and need surgical treatment. Recent clinical studies have shown strong evidence that there is a one-to-one correspondence between chronic OM and the presence of a bacterial biofilm behind the TM. This thesis proposes an approach to investigate bacterial biofilm in the middle ear using two methods, low coherence interferometry (LCI)/optical coherent tomography (OCT) and acoustic measurements. Portable systems were constructed by integrating LCI/OCT techniques with a standard video otoscope to provide depth-resolved optical scattering properties of the middle ear. An automatic algorithm was written to classify the LCI/OCT data to detect the presence of biofilm behind the TM and therefore distinguish the chronic infection. The acoustic measurement provides multi-frequency reflectance and impedance characteristics of the middle ear. These acoustic measurements are then represented by pole-zero plots, which are then analyzed to determine physical acoustic characteristics and to synthesize models of the middle ear. Item withdrawn by Mark Zulauf (zulauf@illinois.edu) on 2012-07-13T17:09:40Z Item was in collections: University of Illinois Theses & Dissertations (ID: 1) No. of bitstreams: 2 1_Nguyen_Cac.docx: 20915824 bytes, checksum: cd2543e5982d45a9603064b4ca866b1d (MD5) Nguyen_Cac.pdf: 3856126 bytes, checksum: f5aec96b40bb07d00ae8f026e06b3824 (MD5) Made available in DSpace on 2012-09-18T21:06:13Z (GMT). No. of bitstreams: 3 Nguyen_Cac.pdf: 3856126 bytes, checksum: f5aec96b40bb07d00ae8f026e06b3824 (MD5) 1_Nguyen_Cac.docx: 20915824 bytes, checksum: cd2543e5982d45a9603064b4ca866b1d (MD5) license.txt: 4060 bytes, checksum: ee93948630eecc60d12b00bba7fa8f32 (MD5) http://hdl.handle.net/2142/34215 en Copyright 2012 Cac Nguyen Middle ear infection Bacterial biofilm Low coherence interferometry Optical coherence tomography Non-invasive assessment of bacterial biofilm in the middle ear using low-coherence interferometry/optical coherence tomography and acoustic measurements Electrical & Computer Eng 1933 Electrical & Computer Engr 1200 University of Illinois at Urbana-Champaign Dissertation Ph.D. PHD:Electr & Computer Eng-UIUC 10KS1200PHD