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Tanner, Kandice Danielle 2012-11-27T22:54:42Z 2012-11-27T22:54:42Z 10000-01-01 2006 Physicists provide significant contributions to the field of Biology and Medical Sciences by applying basic physics principles to the field. Specifically, in this work, we probed the light-matter interactions in the NIR region to understand physiological processes in the mammalian brain. We sought to improve on existing principles and propose a new technique by which we can decipher these processes spectrally. This technique touted to be independent of the light transport regime allowed us to examine the hemodynamics and neuronal activity. The aim was then to test this technique and see if it produces results that were comparable to the well established Fd- NIRS in distinguishing physiological processes. Secondly, we wanted to prove that this technique was light transport regime independent which is not the case for the Fd-NIRS. The cat was chosen as an ideal test subject as its anatomy is such that photons are not fully diffusive before being detected as the total size of the grey matter in the cat is roughly 3mm thick. Additionally, we had a priori information about the activation of the visual cortex as a response to specific stimuli. Submitted by Elias Lopez (erlopez2@illinois.edu) on 2012-11-27T22:54:42Z No. of bitstreams: 1 Tanner_Kandice.pdf: 4484649 bytes, checksum: d6b47440af04faef6a4d336e874d5097 (MD5) Made available in DSpace on 2012-11-27T22:54:42Z (GMT). No. of bitstreams: 1 Tanner_Kandice.pdf: 4484649 bytes, checksum: d6b47440af04faef6a4d336e874d5097 (MD5) Previous issue date: 2006 Item marked as restricted to the 'UIUC Users [automated]' Group (id=2) by Elias Lopez (erlopez2@illinois.edu) on 2012-11-27T22:54:42Z Item is restricted indefinitely. Restriction data tranferred 2014-07-01T11:35:28-05:00 Original Data Group with Access UIUC Users [automated] Release Date: none Reason: Author has not yet granted open access permission Author has not yet granted open access permission U of I Only http://hdl.handle.net/2142/35265 en 2006 Tanner © cat-ology nuerophotonics plantom mammalian light-matter near Infrared (NIR) Fd-NIRS grey matter data analysis self reflectance spectral physiology fast signal visual cortex Cat-ology spectrally resolved neurophotonics in the mammalian brain and phantom studies Score text Physics Physics University of Illinois at Urbana-Champaign Dissertation Ph.D.