2026-09-20T17:41:59Z https://www.ideals.illinois.edu/oai-pmh

oai:www.ideals.illinois.edu:2142/44419 2023-07-11 col_2142_5131 col_2142_8888 com_2142_5130 com_2142_8887 com_2142_234

Bhargava, Rohit Devetter, Brent M. 2013-05-24T22:15:26Z 2013-05-24T22:15:26Z 2015-05-24T10:01:12Z 2013-05 2013-05-24T22:15:26Z 2013-05 Surface-enhanced Raman spectroscopy (SERS) is an ultrasensitive technique with applications ranging from in vitro and in vivo biological sensing to chemical and explosives detection. In this thesis, we explore the design and characterization of suspensions of nanoparticles prior to their use for SERS-based molecular sensing. A major problem in SERS-based measurements is that the signals are often not interpreted quantitatively. Measurements performed in suspension mimic the nanoprobe-to-nanoprobe optical interactions expected to be found in tissues with embedded nanoprobes while particle-level measurements of synthesized nanoparticles provide the molecular basis for calculations. We find that careful consideration of the localized surface plasmon resonance of SERS nanoprobes with respect to laser excitation wavelength is essential for maximizing detectable SERS signal. Additionally, the reporter molecule load per particle depends on synthesis conditions and the shape of the nanoparticles. Together, well-characterized suspensions can be used to understand the molecular and electromagnetic aspects of recorded SERS data. Item withdrawn by Mark Zulauf (zulauf@illinois.edu) on 2013-04-16T22:18:55Z Item was in collections: University of Illinois Theses & Dissertations (ID: 1) No. of bitstreams: 2 DeVetter_Thesis_3.docx: 5493807 bytes, checksum: ffc946f984bb419153889fc84c484ae8 (MD5) Devetter_Brent.pdf: 1565501 bytes, checksum: bd839ba1fe5bffc56826b5194fcdb360 (MD5) Made available in DSpace on 2013-05-24T22:15:26Z (GMT). No. of bitstreams: 2 Brent_Devetter.pdf: 1565529 bytes, checksum: c7f8e005e1da2b7aacb439cf11adce7b (MD5) license.txt: 4064 bytes, checksum: 526e8602856707f14b5d5c0e669745da (MD5) Restriction data tranferred 2014-07-01T11:35:40-05:00 Original Data Group with Access UIUC Users [automated] Release Date: 2015-05-24 17:18:31 UTC Reason: Author requested U of Illinois access only (OA after 2yrs) in Vireo ETD system Item marked as restricted to the 'UIUC Users [automated]' Group (id=2) by Seth Robbins (srobbins@illinois.edu) on 2013-05-24T22:18:42Z Item is restricted until 2015-05-24T22:18:31Z U of I Only Restriction Lifted for Item 44392 on 2015-05-24T10:01:12Z. http://hdl.handle.net/2142/44419 en Copyright 2013 Brent Devetter surface-enhanced Raman spectroscopy gold nanoparticles plasmonics chemical sensing Synthesis and characterization of nanoparticle suspensions: Towards quantitative surface-enhanced Raman spectroscopic sensing text Electrical & Computer Eng 1933 Electrical & Computer Engr 1200 University of Illinois at Urbana-Champaign Thesis M.S. MS:Electr & Computer Eng-UIUC 10KS1200MS