2026-09-20T03:25:35Z https://www.ideals.illinois.edu/oai-pmh

oai:www.ideals.illinois.edu:2142/45541 2023-07-11 col_2142_5163 col_2142_5131 com_2142_5162 com_2142_234 com_2142_5130

Restriction data tranferred 2014-07-01T11:20:34-05:00 Original Data Group with Access UIUC Users [automated] Release Date: 2015-08-22 11:49:27 UTC Reason: Author requested U of Illinois access only (OA after 2yrs) in Vireo ETD system Item marked as restricted to the 'UIUC Users [automated]' Group (id=2) by Seth Robbins (srobbins@illinois.edu) on 2013-08-22T16:49:31Z Item is restricted until 2015-08-22T16:49:27Z U of I Only Restriction Lifted for Item 45523 on 2015-08-22T10:00:54Z. http://hdl.handle.net/2142/45541 en Copyright 2013 Shamira Sridharan prostate cancer quantitative phase imaging (QPI) spatial light interference microscopy (SLIM) Gleason grading nucleus Prostate tissue diagnosis using quantitative phase imaging techniques text Popescu, Gabriel Sridharan, Shamira 2013-08-22T16:47:10Z 2013-08-22T16:47:10Z 2015-08-22T10:00:54Z 2013-08 2013-08-22T16:47:10Z 2013-08 The lifetime risk of a man getting diagnosed with prostate cancer is 1 in 6. The diagnosis is made by the pathologist using staining methods and immunohistochemical markers to detect malignancy on tissue biopsy sections. Quantitative phase imaging methods eliminate the need for stains and markers. It exploits the intrinsic contrast from the refractive index differences in tissue. The quantitative nature of this technique eliminates inter-observer variability. QPI is sensitive to sub-nanometer level changes in tissue architecture. Light scattering information is also accessible from QPI images since it records both the amplitude and the phase of light that passes through the sample. In this thesis, I show the ability of QPI to distinguish between cancerous and benign samples. I also show its ability to detect changes in stroma and nuclei through different stages of prostate cancer progression that are not detectable using conventional methods. Item withdrawn by Alexis Thompson (athmpsn1@illinois.edu) on 2013-07-11T19:31:27Z Item was in collections: University of Illinois Theses & Dissertations (ID: 1) No. of bitstreams: 1 Sridharan_Shamira.pdf: 2152468 bytes, checksum: c23ceb7df8aff17e68389ebefa6e5e74 (MD5) Made available in DSpace on 2013-08-22T16:47:10Z (GMT). No. of bitstreams: 2 Shamira_Sridharan.pdf: 2152513 bytes, checksum: 40b9bf894217cf1802648259a6a4bd4d (MD5) license.txt: 4066 bytes, checksum: bab28e34c7e1bbd37cb837b6c2f5653f (MD5) Bioengineering 1343 Bioengineering 0408 University of Illinois at Urbana-Champaign Thesis M.S. MS:Bioengineering - UIUC 10KS0408MS