2026-09-18T20:14:31Z https://www.ideals.illinois.edu/oai-pmh

oai:www.ideals.illinois.edu:2142/46580 2023-07-11 col_2142_5131 col_2142_8888 com_2142_5130 com_2142_8887 com_2142_234

Boppart, Stephen A. South, Fredrick A. 2014-01-16T17:54:50Z 2014-01-16T17:54:50Z 2016-02-21T11:02:21Z 2013-12 2014-01-16T17:54:50Z 2013-12 Successful treatment of most breast cancers requires surgical removal of the tumor. The current standard-of-care does not provide any tools for real-time assessment of the tumor cavity. Optical coherence tomography (OCT) has previously been developed for real-time intraoperative use in hopes of aiding tumor margin assessment. While there has been much success, it remains difficult to distinguish between normal stroma tissue and breast cancer. Polarization-sensitive optical coherence tomography (PS-OCT) is an extension of OCT that measures both the intensity and polarization of light returning from the tissue. PS-OCT is sensitive to changes in collagen structure and may provide additional contrast between normal and diseased tissue. This thesis reports the development of a real-time PS-OCT system using a high-speed swept-source laser and parallel processing on a graphics processing unit (GPU). Results of a preliminary imaging study are also reported, demonstrating that PS-OCT provides enhanced contrast between previously indistinguishable fibrous stroma and invasive ductal carcinoma (IDC). Item withdrawn by Mark Zulauf (zulauf@illinois.edu) on 2013-12-11T14:27:57Z Item was in collections: University of Illinois Theses & Dissertations (ID: 1) No. of bitstreams: 3 South_Fredrick.docx: 13653786 bytes, checksum: 8602aedfbfc50b586a5b2bf9cfdf6273 (MD5) south1_MS_v05.pdf: 3416542 bytes, checksum: a779501f43a968c7015fef1d011e1730 (MD5) South_Fredrick.pdf: 3416542 bytes, checksum: a779501f43a968c7015fef1d011e1730 (MD5) Made available in DSpace on 2014-01-16T17:54:50Z (GMT). No. of bitstreams: 3 Fredrick_South.pdf: 3416542 bytes, checksum: a779501f43a968c7015fef1d011e1730 (MD5) South_Fredrick.docx: 13653786 bytes, checksum: 8602aedfbfc50b586a5b2bf9cfdf6273 (MD5) license.txt: 4062 bytes, checksum: a7d1440e8c8cf17a1c2baf9697d7f30c (MD5) Restriction data tranferred 2014-07-01T11:10:03-05:00 Original Data Group with Access UIUC Users [automated] Release Date: 2016-02-21 14:58:26 UTC Reason: Requested restricted access and approved by the Graduate College sshreeve 02/21/2014 Item marked as restricted to the 'UIUC Users [automated]' Group (id=2) by Sarah Shreeves (sshreeve@illinois.edu) on 2014-02-21T20:58:26Z Item is restricted until 2016-02-21T20:58:26Z U of I Only Restriction Lifted for Item 46600 on 2016-02-21T11:02:21Z. http://hdl.handle.net/2142/46580 en Copyright 2013 Fredrick South biomedical imaging optical coherence tomography breast cancer polarization High-speed polarization-sensitive optical coherence tomography: toward intraoperative cancer imaging text Electrical & Computer Eng 1933 Electrical & Computer Engr 1200 University of Illinois at Urbana-Champaign Thesis M.S. MS:Electr & Computer Eng-UIUC 10KS1200MS