2026-09-22T02:25:22Z https://www.ideals.illinois.edu/oai-pmh

oai:www.ideals.illinois.edu:2142/46940 2023-07-11 col_2142_5163 col_2142_5131 com_2142_5162 com_2142_234 com_2142_5130

Bashir, Rashid Keller, Katrina 2014-01-16T18:27:06Z 2014-01-16T18:27:06Z 2016-01-16T11:01:04Z 2013-12 2014-01-16T18:27:06Z 2013-12 Studying cells at the individual level is incredibly important for understanding underlying mechanisms for growth, cell cycle control, cell mass, cell adhesion to surfaces, and ultimately the nature of cancer cells. A resonant pedestal sensor was used to study single, adherent cells non-invasively. This measurement tool was preferred over other methods because the mass uniformity of its surface is independent of the location of the cell. Images were taken at each time point to aid in the data processing. This resonant pedestal sensor was fabricated in a cleanroom facility and used to measure the mass of an individual MDA-MB-231 (metastatic breast cancer) cell. The noisy mass measurements were subjected to two different processing methods: Savitzky-Golay and Moving Average. Our main goal in performing these two techniques was to determine the most appropriate processing method for our data. We found the Savitzky-Golay method to be more favorable than the moving average to interpret the MDA-MB-231 cell growth curves. Once outlier exclusion was performed on the data, a positive linear relationship was visible and we were able to calculate the percent change of this cell type: 1% of cell mass is increased per hour. Item withdrawn by Mark Zulauf (zulauf@illinois.edu) on 2013-12-13T15:53:42Z Item was in collections: University of Illinois Theses & Dissertations (ID: 1) No. of bitstreams: 1 Keller_Katrina.pdf: 16227573 bytes, checksum: 5aeba34aba56099ddd32aaaca05e0139 (MD5) Made available in DSpace on 2014-01-16T18:27:06Z (GMT). No. of bitstreams: 2 Katrina_Keller.pdf: 16241499 bytes, checksum: 8626f9f798eea560d8760a4264552e34 (MD5) license.txt: 4064 bytes, checksum: 83b101e76a57fa34b8b8679f4567b31e (MD5) Item marked as restricted to the 'Administrator' Group (id=1) by Seth Robbins (robbins.sd@gmail.com) on 2014-01-16T18:27:41Z Item is restricted until 2016-01-16T18:27:27Z Restriction data tranferred 2014-07-01T11:36:53-05:00 Original Data Group with Access Administrator Release Date: 2016-01-16 12:27:27 UTC Reason: Author requested closed access (OA after 2yrs) in Vireo ETD system Limited Restriction Lifted for Item 46959 on 2016-01-16T11:01:04Z. http://hdl.handle.net/2142/46940 en Copyright 2013 Katrina Keller Microelectromechanical systems (MEMS) Cancer Using resonant MEMS pedestal sensors and filtering techniques to determine the growth curve of MDA-MB-231, metastatic breast cancer cells text Bioengineering 1343 Bioengineering 0408 University of Illinois at Urbana-Champaign Thesis M.S. PHD: Bioengineering-UIUC 10KS0408PHD