2026-09-21T21:05:27Z https://www.ideals.illinois.edu/oai-pmh

oai:www.ideals.illinois.edu:2142/50497 2023-07-11 col_2142_5131 col_2142_14798 com_2142_5130 com_2142_686 com_2142_397

U of I Only Restriction Lifted for Item 50608 on 2016-09-22T20:59:19Z. http://hdl.handle.net/2142/50497 en Copyright 2014 Fizza Mughal Metabolic Networks Caetano-Anolles, Gustavo Mughal, Fizza 2014-09-16T17:18:02Z 2014-09-16T17:18:02Z 2016-09-22T20:59:19Z 2014-08 2014-09-16 2014-08 The metabolic MANET is an online resource that incorporates data from KEGG, SCOP and structural phylogenomics. A revised version of MANET was here produced that not only uses recent data from KEGG and SCOP, but also evolutionary information of fold families derived from structural phylogenomic reconstructions. In addition, a fourth data source, PDBsum, has been added to this resource amalgamation, which serves to provide the link between enzyme and PDB information. With the introduction of fold family data, the updated version offers a 10-fold increase of data entries compared to the current version that is based on fold data. The global analysis of metabolism at mesonetwork as well as the subnetwork level puts forth interesting patterns of enzyme sharing that lend support to the patchwork model of metabolic evolution. The sharing patterns we identify are not just restricted to subnetworks. Instead, they transcend mesonetwork boundaries. Item withdrawn by Laura Spradlin (lspradl2@illinois.edu) on 2014-07-25T18:01:53Z Item was in collections: University of Illinois Theses & Dissertations (ID: 1) No. of bitstreams: 2 Mughal_Fizza.docx: 5840878 bytes, checksum: 296bff7afa9c7abc3898fd3aa7a252d9 (MD5) Mughal_Fizza.pdf: 4495428 bytes, checksum: e2776cd3de38157af7c4131fa8d293e8 (MD5) Made available in DSpace on 2014-09-16T17:18:02Z (GMT). No. of bitstreams: 3 Fizza_Mughal.pdf: 4495428 bytes, checksum: e2776cd3de38157af7c4131fa8d293e8 (MD5) Mughal_Fizza.docx: 5840878 bytes, checksum: 296bff7afa9c7abc3898fd3aa7a252d9 (MD5) license.txt: 4062 bytes, checksum: a2fe28bf300627509a2e6d84331a7fbd (MD5) Embargo set by: Seth Robbins for item 50608 Lift date: 2016-09-16T17:18:17Z Reason: Author requested U of Illinois access only (OA after 2yrs) in Vireo ETD system Enzyme Evolution Phylogenomics Protein Domain MANET and the evolution, structure and function of biological networks text Crop Sciences 1802 Bioinformatics 4026 University of Illinois at Urbana-Champaign Thesis M.S. MS: Bioinformatics: CropS-UIUC 10KS5100MS