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oai:www.ideals.illinois.edu:2142/50635 2023-07-11 col_2142_5131 col_2142_5163 com_2142_5130 com_2142_5162 com_2142_234

Sutton, Bradley P. Wilder, Hailey 2014-09-16T17:24:35Z 2014-09-16T17:24:35Z 2014-08 2014-09-16 2014-08 Magnetic Resonance Spectroscopy (MRS) is a useful tool for obtaining information about metabolite concentrations. Information that can be extrapolated from these concentrations may be absolute or relative in nature, depending on the availability of an internal reference. For example, MR Thermometry using Single Voxel Spectroscopy (SVS) utilizes the water peak as an internal reference to observed metabolites offering a means of interpreting absolute metabolite values. On the other hand, metabolite mapping is best performed by utilizing water suppression since the water peak is of a magnitude 10^4 times larger than metabolite peaks. In this case metabolite information is characterized relative to other metabolites and a metabolite of interest is given as a percentage. Sensitivity in MRS is of the utmost concern since metabolites appear at such small concentration in the brain. Thus, metabolite peak position using a Guassian and Hamming filters and the adaptation of chemical shift imaging from 2D to 3D is useful in obtaining more precise information. Herein, it is shown that both absolute and relative quanti cation can be improved through, respectively, frequency filters and increased dimensional acquisition. Item withdrawn by Laura Spradlin (lspradl2@illinois.edu) on 2014-07-21T15:36:48Z Item was in collections: University of Illinois Theses & Dissertations (ID: 1) No. of bitstreams: 1 Wilder_Hailey.pdf: 1652049 bytes, checksum: 66b16efcfa572f97067b23d3af76f6fe (MD5) Made available in DSpace on 2014-09-16T17:24:35Z (GMT). No. of bitstreams: 2 Hailey_Wilder.pdf: 1652460 bytes, checksum: 3a7e1f19ca1f91a00d7e86f51e1dc8fd (MD5) license.txt: 4063 bytes, checksum: 1e6173924ae2ebf2ae55713fd44a91d4 (MD5) http://hdl.handle.net/2142/50635 en Copyright 2014 Hailey Wilder Magnetic Resonance Spectroscopy Imaging (MRSI) Single Voxel Spectroscopy (SVS) Thermometry 2d 3d chemical shift image (CSI) Multi-Dimensional Chemical Shift Imaging (CSI) Segmentation and Metabolite Mapping Magnetic resonance spectroscopy: techniques and applications in thermometry and metabolite mapping text Bioengineering 1343 Bioengineering 0408 University of Illinois at Urbana-Champaign Thesis M.S. MS:Bioengineering - UIUC 10KS0408MS