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10000-01-01 1984 Dellinger, John Albert 2014-12-16T06:35:36Z 2014-12-16T06:35:36Z 1984 Atropine sulfate is an important therapeutic agent for treating anticholinesterase toxicosis, but atropine also is a strong anticholinergic drug with side effects. Twenty volunteers received a placebo control and atropine doses of 0.5, 1.0, 2.0, and 4.0 mg/75 kg in a Latin Square double blind design, and effects were monitored for 3 hr post-injection. Primary task performance on six root mean square errors were tested in a multivariate analysis of variance, and the treatment effect was significant (F(24, 1236) = 5.95, p .10), (b) "difficulty swallowing," ED50 = 2.11 mg ((chi)('2)(1, N = 4) = 2.11, p > .10), (c) tachycardia, ED50 = 2.58 mg ((chi)('2)(1, N = 4) = 2.74, p .10), (e) photophobia, ED50 = 4.28 mg ((chi)('2)(1, N = 4) = 4.38, p .10). Made available in DSpace on 2014-12-16T06:35:36Z (GMT). No. of bitstreams: 1 8502125.pdf: 4074974 bytes, checksum: 48066e89c7cb1e726b9b410d1c1013fc (MD5) Previous issue date: 1984 Embargo set by: Seth Robbins for item 71483 Lift date: Forever Reason: Restricted to the U of I community idenfinitely during batch ingest of legacy ETDs Restricted to the U of I community idenfinitely during batch ingest of legacy ETDs U of I Only 125 p. Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 1984. http://hdl.handle.net/2142/71317 (UMI)AAI8502125 Health Sciences, Pharmacology The Effects of Atropine Sulfate on Flight Simulator Performance and on Respiratory-Heart Period Interactions (Human, Electrocardiogram, Organophosphorous) text Veterinary Medical Science Veterinary Medical Science University of Illinois at Urbana-Champaign Dissertation Ph.D.