2026-09-22T01:01:52Z https://www.ideals.illinois.edu/oai-pmh

oai:www.ideals.illinois.edu:2142/72990 2023-07-11 col_2142_5131 col_2142_13836 com_2142_5130 com_2142_13835 com_2142_234

Rogers, John A. Rogers, John A. Zuo, Jian-Min Li, Xiuling Dillon, Shen J. Xu, Lizhi 2015-01-21T19:55:25Z 2015-01-21T19:55:25Z 2017-01-22T10:15:27Z 2014-12 2015-01-21 2014-12 Developments in materials and mechanics for flexible electronics create opportunities for building novel electronic devices that physically interface with the human body, its organs and various tissues. Among the wide variety of application scenarios, integration with the heart represents a case that is both promising and challenging. Conformal electronic systems for monitoring physiological activity and for delivering therapies are critically important for both basic and clinical cardiology. The complex 3D geometry and time-dynamic deformations of the heart, however, create difficulties in establishing intimate, non-constraining interfaces between medical electronics and cardiac structures. Here we present advanced materials, mechanical designs and fabrication approaches that yield classes of 3D conformal electronic platforms with novel capabilities in cardiac physiological mapping and stimulation. Designs for both individual sensors/actuators components and overall device platforms are involved. The materials selections for sensors/actuators components include conductive composite for tactile sensors, silicon nanomembranes for strain gauges, iridium oxide for pH sensors, gallium nitride and gallium arsenide for optoelectronics, metal thin films for temperature sensing, and nanotextured electrode coatings for characterizing electrical activities. Careful mechanical design and fractal concepts enable device characteristics that are compatible with the intrinsic cardiac physiology. Novel device platforms, including multifunctional balloon catheters and 3D multifunctional integumentary membranes, are developed to allow integration of these components in systems that yield critical functionalities for biomedical applications. Animal experiments demonstrate the operational capabilities. The results suggest routes for fabricating advanced electronic materials and devices with 3D formats and create methodological possibilities for both basic physiological research and clinical medicine. Item withdrawn by Laura Spradlin (lspradl2@illinois.edu) on 2014-11-21T14:22:15Z Item was in collections: University of Illinois Theses & Dissertations (ID: 1) No. of bitstreams: 1 Xu_Lizhi.pdf: 6472585 bytes, checksum: 4f9e07e827ee934ab39ae95960819e5e (MD5) Made available in DSpace on 2015-01-21T19:55:25Z (GMT). No. of bitstreams: 1 Lizhi_Xu.pdf: 6473811 bytes, checksum: 021dca5cbf3358aa0f29536119d904eb (MD5) Embargo set by: Seth Robbins for item 73179 Lift date: 2017-01-21T19:56:18Z Reason: Author requested U of Illinois access only (OA after 2yrs) in Vireo ETD system U of I Only Restriction Lifted for Item 73179 on 2017-01-22T10:15:27Z. http://hdl.handle.net/2142/72990 en Copyright 2014 Lizhi Xu Electronic materials Micro and nano fabrication Flexible and stretchable electronics Bio-medical applications Materials and designs for 3D conformal electronics with capabilities in cardiac mapping and stimulation text Materials Science & Engineerng 1919 Materials Science & Engr 0130 University of Illinois at Urbana-Champaign Dissertation Ph.D. PHD:Materials Sci & Engr -UIUC 10KS0130PHD