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oai:www.ideals.illinois.edu:2142/80528 2023-07-11 col_2142_5131 col_2142_8859 com_2142_5130 com_2142_8858 com_2142_234

Clegg, Robert M. Majumdar, Zigurts Krishna 2015-09-25T20:02:56Z 2015-09-25T20:02:56Z 10000-01-01 2005 2005 The second half of this thesis is independent of the above. We present the design, construction and implementation of micro-fabricated, continuous-flow, turbulent mixing devices that can mix two or three fluids to complete homogeneity on the molecular scale in the microsecond range. The prototypical designs are compact, portable, simple to fabricate and consume smaller sample volumes than current technology. We characterize the turbulent mixing process in microfluidic channels with fluorescence intensity and lifetime imaging and show that both the dependence of mixing times and pressure drop on the flow velocity and Reynolds number agree well with theoretical expectations for turbulent pipe flow. The novelties in this work are: the new methods of fabrication which enable production of three-dimensional geometries in glass with micro-fabrication methods, the implementation of turbulent mixing and measurement at microsecond timescales and showing the ability to generalize theoretical expectations for turbulence in pipes with micrometer scale dimensions. Made available in DSpace on 2015-09-25T20:02:56Z (GMT). No. of bitstreams: 2 license.txt: 4848 bytes, checksum: 96035ab3f5e1c23cc7138a224ce498bd (MD5) 3202138.pdf: 5455853 bytes, checksum: 145a8e1d835e910034c370181ac8ae30 (MD5) Previous issue date: 2005 Embargo set by: Seth Robbins for item 81810 Lift date: Forever Reason: Restricted to the U of I community idenfinitely during batch ingest of legacy ETDs Restricted to the U of I community idenfinitely during batch ingest of legacy ETDs U of I Only 193 p. Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 2005. http://hdl.handle.net/2142/80528 (MiAaPQ)AAI3202138 eng Biology, Molecular Measurement of Internal Movements of the Escherichia Coli Ribosome Using Forster Resonance Energy Transfer and Microsecond, Continuous -Flow Turbulent Mixing in Micro-Fabricated Devices text Physics Physics University of Illinois at Urbana-Champaign Dissertation Ph.D.