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oai:www.ideals.illinois.edu:2142/81283 2023-07-11 col_2142_5131 col_2142_8888 com_2142_5130 com_2142_8887 com_2142_234

Andrew G. Webb Lam, Michael Mun-Foong 2015-09-25T20:10:23Z 2015-09-25T20:10:23Z 10000-01-01 1999 1999 This thesis presents a number of improvements and additions, both theoretical and experimental, to NMR microspectroscopy that expand considerably its practical application to studying mass-limited samples. Microcoils have been designed for higher magnetic fields (500 MHz) and also now incorporate a lock channel for longer two-dimensional (2D) experiments. Reference deconvolution and wavelet noise reduction have been used to address lineshape distortion and low signal-to-noise found in NMR microspectroscopy spectra. Double quantum filtered correlated spectroscopy (DQF-COSY) allows signals from selected components in the sample to be isolated. Inclusion of gradients in the microcoil probe greatly enhanced DQF-COSY experiments and enabled a host of other selective editing sequences to be run. Finally experimental measurements and theoretical predictions were shown regarding the effects of restricted diffusion in microcoils. Diffusion-ordered spectroscopy (DOSY) experiments, which allow spectral simplification arising from differences in diffusion coefficient, coupled with conventional chemical shift and scalar coupling differences, were shown for the first time for mass-limited samples. Made available in DSpace on 2015-09-25T20:10:23Z (GMT). No. of bitstreams: 2 license.txt: 4848 bytes, checksum: 96035ab3f5e1c23cc7138a224ce498bd (MD5) 9921709.pdf: 5859503 bytes, checksum: c482cd4a02e4eadd096fa2f2828b0dc6 (MD5) Previous issue date: 1999 Embargo set by: Seth Robbins for item 82564 Lift date: Forever Reason: Restricted to the U of I community idenfinitely during batch ingest of legacy ETDs Restricted to the U of I community idenfinitely during batch ingest of legacy ETDs U of I Only 147 p. Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 1999. http://hdl.handle.net/2142/81283 (MiAaPQ)AAI9921709 eng Chemistry, Analytical High-Resolution Nuclear Magnetic Resonance Microspectroscopy text Electrical Engineering Electrical Engineering University of Illinois at Urbana-Champaign Dissertation Ph.D.