2026-09-20T10:26:59Z https://www.ideals.illinois.edu/oai-pmh

oai:www.ideals.illinois.edu:2142/82377 2023-07-11 col_2142_5131 col_2142_11615 com_2142_5130 com_2142_9130 com_2142_8903

Deborah Leckband Prakasam, Anil Kumar 2015-09-25T20:43:25Z 2015-09-25T20:43:25Z 10000-01-01 2005 2005 All three of the cadherins investigated in this thesis formed strong heterophilic bonds at three ectodomain alignments. Of the three, the inner bond (strongest) corresponding to full ectodomain overlap, did not exhibit much variation in either the homophilic or the heterophilic interactions. The two outer bonds (weaker) which are attributed to EC2/EC2 and EC1/EC1 binding, exhibit the greatest variation in bond strengths. In contrast to current thinking, these data show that there is no energetic preference for homophilic over heterophilic binding that would explain the cell sorting behavior. Made available in DSpace on 2015-09-25T20:43:25Z (GMT). No. of bitstreams: 2 license.txt: 4848 bytes, checksum: 96035ab3f5e1c23cc7138a224ce498bd (MD5) 3199117.pdf: 3558327 bytes, checksum: 3fdc8805739876c06cb7067776112b59 (MD5) Previous issue date: 2005 Embargo set by: Seth Robbins for item 83658 Lift date: Forever Reason: Restricted to the U of I community idenfinitely during batch ingest of legacy ETDs Restricted to the U of I community idenfinitely during batch ingest of legacy ETDs U of I Only 144 p. Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 2005. http://hdl.handle.net/2142/82377 (MiAaPQ)AAI3199117 eng Biophysics, General Homophilic and Heterophilic Interactions Among Cadherin Cell Adhesion Molecules text Chemical Engineering Chemical Engineering University of Illinois at Urbana-Champaign Dissertation Ph.D.