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oai:www.ideals.illinois.edu:2142/82414 2023-07-11 col_2142_5131 col_2142_11615 com_2142_5130 com_2142_9130 com_2142_8903

Leckband, Deborah E. Kenis, Paul J.A. Silvestre, Jonathan 2015-09-25T20:43:38Z 2015-09-25T20:43:38Z 10000-01-01 2008 2008 Furthermore, these studies quantified the relative effects of E-cadherin expression and adhesive ligation on the migration velocities of mammary breast tumor cells. Micropatterned proteins were used to titrate the relative effects of E-cadherin and Fibronectin on the migration velocities of the metastatic mammary epithelial tumor cells MDA-MB-231. These investigations show that increased E-cadherin expression reduces cell motility by both adhesion-dependent and adhesion-independent mechanisms. By controlling both the substratum composition and E-cadherin expression we defined conditions that favor either the adhesion-independent or the adhesion-dependent mechanism of motility suppression. Made available in DSpace on 2015-09-25T20:43:38Z (GMT). No. of bitstreams: 2 license.txt: 4848 bytes, checksum: 96035ab3f5e1c23cc7138a224ce498bd (MD5) 3337924.pdf: 5953288 bytes, checksum: 7446f51c2714d0c0431c0d1cc317b06f (MD5) Previous issue date: 2008 Embargo set by: Seth Robbins for item 83695 Lift date: Forever Reason: Restricted to the U of I community idenfinitely during batch ingest of legacy ETDs Restricted to the U of I community idenfinitely during batch ingest of legacy ETDs U of I Only 153 p. Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 2008. http://hdl.handle.net/2142/82414 (MiAaPQ)AAI3337924 eng Engineering, Chemical Microfluidic Platforms for Investigating Cell Migration text Chemical Engineering Chemical Engineering University of Illinois at Urbana-Champaign Dissertation Ph.D.