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oai:www.ideals.illinois.edu:2142/83594 2023-07-11 col_2142_5131 col_2142_14771 com_2142_5130 com_2142_685 com_2142_397

Lewin, Harris A. Larson, Joshua H. 2015-09-25T21:08:21Z 2015-09-25T21:08:21Z 10000-01-01 2006 2006 Ten divergent homologs were identified using a subtractive bioinformatic analysis of 12,614 cattle placenta ESTs followed by comparative, evolutionary and gene expression studies. Eight have not been identified previously. These were named: CSSMST1, CIST1, HAVCRNDP, PRP8, PRP9, PRP11, SECTM1A and SECTM1B. Nucleotide substitution analysis provided evidence for positive selection in members of the PRP gene family, SECTM1A and SECTM1B. Gene expression profiles, motif predictions, and annotations of homologous sequences indicate immunological and reproductive functions of the divergent homologs. The genes identified in this experiment are thus of evolutionary and physiological importance and may have a role in placental adaptations. Made available in DSpace on 2015-09-25T21:08:21Z (GMT). No. of bitstreams: 2 license.txt: 4848 bytes, checksum: 96035ab3f5e1c23cc7138a224ce498bd (MD5) 3223637.pdf: 2787263 bytes, checksum: 727223a6b74edca988709c88b7f70c3b (MD5) Previous issue date: 2006 Embargo set by: Seth Robbins for item 84875 Lift date: Forever Reason: Restricted to the U of I community idenfinitely during batch ingest of legacy ETDs Restricted to the U of I community idenfinitely during batch ingest of legacy ETDs U of I Only 100 p. Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 2006. http://hdl.handle.net/2142/83594 (MiAaPQ)AAI3223637 eng Biology, Bioinformatics The Discovery and Evolutionary Analysis of Divergent Homologs Involved in Cattle Immune and Reproductive Biology text Animal Sciences Animal Sciences University of Illinois at Urbana-Champaign Dissertation Ph.D.