2026-09-22T04:16:58Z https://www.ideals.illinois.edu/oai-pmh

oai:www.ideals.illinois.edu:2142/84188 2023-07-11 col_2142_5131 col_2142_14789 com_2142_5130 com_2142_14788 com_2142_8903

Kenneth S. Suslick Jean-Jacques Toublan, Farah 2015-09-25T22:13:23Z 2015-09-25T22:13:23Z 10000-01-01 2005 2005 In this thesis, I have developed methods to systematically modify the core, shell, and surface of the protein microspheres. In addition, I have shown that the size of these spheres can be reduced from the micron scale to the nano scale. These modifications have thus improved the versatility and the applicability of the microspheres to a variety of applications. Modifications involving nanoparticles have resulted in the first class of optical contrast agents for optical coherence tomography (OCT). Modifications with receptor specific peptides have generated microspheres that can be targeted to tumor cells. And finally, modifications of the microspheres with nucleic acids have opened the door to new applications in gene therapy. Made available in DSpace on 2015-09-25T22:13:23Z (GMT). No. of bitstreams: 2 license.txt: 4848 bytes, checksum: 96035ab3f5e1c23cc7138a224ce498bd (MD5) 3199030.pdf: 4015282 bytes, checksum: dad807df6e92faa1cd4ae8bf398d2a8d (MD5) Previous issue date: 2005 Embargo set by: Seth Robbins for item 85469 Lift date: Forever Reason: Restricted to the U of I community idenfinitely during batch ingest of legacy ETDs Restricted to the U of I community idenfinitely during batch ingest of legacy ETDs U of I Only 199 p. Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 2005. http://hdl.handle.net/2142/84188 (MiAaPQ)AAI3199030 eng Engineering, Biomedical Methods to Tailor Protein Microspheres for Biomedical Applications text Chemistry Chemistry University of Illinois at Urbana-Champaign Dissertation Ph.D.