2026-09-21T04:31:38Z https://www.ideals.illinois.edu/oai-pmh

oai:www.ideals.illinois.edu:2142/84264 2023-07-11 col_2142_5131 col_2142_14789 com_2142_5130 com_2142_14788 com_2142_8903

Mary S. Gin Schmidt, Emily Grace 2015-09-25T22:13:43Z 2015-09-25T22:13:43Z 10000-01-01 2007 2007 To probe the correlation between pore size and ion selectivity, a channel with an alpha-cyclodextrin macrocycle was synthesized and its transport properties were compared with those of an analogous channel with a larger beta-cyclodextrin pore. The anion transport profile of the alpha-cyclodextrin channel (ClO 4- > I- > Br- > NO3- > Cl-) differed from that of its beta-cyclodextrin counterpart (ClO4 - > I- > NO3- > Br- > Cl-) in the order of bromide and nitrate transport rates. While quantitative comparisons could not be made between the rates of ion transport through the alpha- and beta-cyclodextrin channels, a number of qualitative differences were observed between the two sets of transport data. Namely, the smaller pore of the alpha-cyclodextrin channel appeared to bind Cl- in such a way as to restrict Na+ transport. In addition, the larger I- and ClO4- ions seemed to pass through channel-induced membrane defects rather than through the smaller pore of the alpha-cyclodextrin channel. Made available in DSpace on 2015-09-25T22:13:43Z (GMT). No. of bitstreams: 2 license.txt: 4848 bytes, checksum: 96035ab3f5e1c23cc7138a224ce498bd (MD5) 3270020.pdf: 3775043 bytes, checksum: e5709f3ed821baafa44de1490d23c8df (MD5) Previous issue date: 2007 Embargo set by: Seth Robbins for item 85545 Lift date: Forever Reason: Restricted to the U of I community idenfinitely during batch ingest of legacy ETDs Restricted to the U of I community idenfinitely during batch ingest of legacy ETDs U of I Only 154 p. Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 2007. http://hdl.handle.net/2142/84264 (MiAaPQ)AAI3270020 eng Chemistry, Organic Synthesis and Study of Biomimetic Ion Channels: (1) Toward the Development of a Cyclic Peptide-Based Redox-Gated Channel, and (2) Investigations Into the Effect of Pore Size on the Ion Selectivity of an Aminocyclodextrin Channel text Chemistry Chemistry University of Illinois at Urbana-Champaign Dissertation Ph.D.