2026-09-21T12:53:23Z https://www.ideals.illinois.edu/oai-pmh

oai:www.ideals.illinois.edu:2142/84316 2023-07-11 col_2142_5131 col_2142_14789 com_2142_5130 com_2142_14788 com_2142_8903

Katzenellenbogen, John A. LaFrate, Andrew 2015-09-25T22:13:55Z 2015-09-25T22:13:55Z 10000-01-01 2008 2008 The synthesis of steroidal bivalent ligands for ER is also reported. Two estradiol molecules were connected through a phenylethynyl linkage with chemical tethers of varying composition and length. The binding properties of the bivalent ligands for ER were measured. Moderate relative binding affinities were obtained and in some cases biphasic binding curves were observed. Made available in DSpace on 2015-09-25T22:13:55Z (GMT). No. of bitstreams: 2 license.txt: 4848 bytes, checksum: 96035ab3f5e1c23cc7138a224ce498bd (MD5) 3337835.pdf: 2011764 bytes, checksum: 344ccf8b5b577f2edd7da8e981618303 (MD5) Previous issue date: 2008 Embargo set by: Seth Robbins for item 85597 Lift date: Forever Reason: Restricted to the U of I community idenfinitely during batch ingest of legacy ETDs Restricted to the U of I community idenfinitely during batch ingest of legacy ETDs U of I Only 137 p. Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 2008. http://hdl.handle.net/2142/84316 (MiAaPQ)AAI3337835 eng Health Sciences, Oncology Synthesis and Biological Evaluation of Coactivator Binding Inhibitors and Bivalent Ligands for the Estrogen Receptor text Chemistry Chemistry University of Illinois at Urbana-Champaign Dissertation Ph.D.