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Switzer, Robert L. Meng, Qi 2015-09-25T22:27:54Z 2015-09-25T22:27:54Z 10000-01-01 2002 2002 I propose that a trans-acting regulatory protein binds to the pyrG GGGC and GCUCCC sequences when intracellular CTP levels are low, which prevents the formation of the terminator and permits transcription readthrough. When intracellular CTP levels are high, I propose the regulatory protein dissociates from the pyrG leader RNA thereby allowing terminator formation and transcription termination. Made available in DSpace on 2015-09-25T22:27:54Z (GMT). No. of bitstreams: 2 license.txt: 4848 bytes, checksum: 96035ab3f5e1c23cc7138a224ce498bd (MD5) 3070387.pdf: 7470418 bytes, checksum: 76562993eea87d5235fd83d37c9c0bd3 (MD5) Previous issue date: 2002 Embargo set by: Seth Robbins for item 86069 Lift date: Forever Reason: Restricted to the U of I community idenfinitely during batch ingest of legacy ETDs Restricted to the U of I community idenfinitely during batch ingest of legacy ETDs U of I Only 159 p. Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 2002. http://hdl.handle.net/2142/84788 (MiAaPQ)AAI3070387 eng Biology, Microbiology Transcriptional Regulation of the Bacillus Subtilis pyrG Gene Encoding Cytidine Triphosphate Synthetase text Biochemistry Biochemistry University of Illinois at Urbana-Champaign Dissertation Ph.D.