2026-09-21T10:42:48Z https://www.ideals.illinois.edu/oai-pmh

oai:www.ideals.illinois.edu:2142/85487 2023-07-11 col_2142_5131 col_2142_14828 com_2142_5130 com_2142_14827 com_2142_14793 com_2142_8903

Thomas J. Anastasio Dow, Ernst Russell 2015-09-25T22:46:14Z 2015-09-25T22:46:14Z 10000-01-01 1999 1999 The vestibular-ocular reflex (VOR) is a plastic system found in vertebrates which produces eye rotations that compensate for head rotations. Simultaneous motion and vision are thus possible since the reflex keeps vision from becoming bluffed during movement. Low-frequency rotations, whether actual, such as those experienced on a ship, or perceived, such as those due to injury, can cause nausea. The VOR prevents nausea by suppressing the response to repeated low-frequencies rotations (i.e. habituation). Previous researchers decreased the time constant of the VOR high-pass filter model to simulate habituation, suggesting that habituation is a general phenomena. The present experiments in goldfish show that habituation is both nonlinear and nonstationary and is quite effective at low-frequencies. Habituation is also frequency-specific and cannot be modeled as a high-pass filter. Instead, the gain and phase changes following habituation have properties that are similar to a band-pass filter. Furthermore, the gain (eye velocity/head velocity) at one frequency can be dependent on whether or not it is superimposed on another frequency, limiting linear systems analysis. This suggests that the VOR can demodulate the frequencies present in head rotations as it can selectively suppress the response at one frequency, depending on the context. These and other findings presented here suggest that habituation is more sensitive to rotational context than previously believed. Made available in DSpace on 2015-09-25T22:46:14Z (GMT). No. of bitstreams: 2 license.txt: 4848 bytes, checksum: 96035ab3f5e1c23cc7138a224ce498bd (MD5) 9921681.pdf: 7692181 bytes, checksum: f00fd27dcc75bec75045f91d63159cca (MD5) Previous issue date: 1999 Embargo set by: Seth Robbins for item 86768 Lift date: Forever Reason: Restricted to the U of I community idenfinitely during batch ingest of legacy ETDs Restricted to the U of I community idenfinitely during batch ingest of legacy ETDs U of I Only 132 p. Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 1999. http://hdl.handle.net/2142/85487 (MiAaPQ)AAI9921681 eng Biology, Animal Physiology Habituation of the Goldfish Vestibulo-Ocular Reflex Is Frequency Specific and Nonlinear: An Experimental and Modeling Study text Biophysics and Computational Biology Biophysics and Computational Biology University of Illinois at Urbana-Champaign Dissertation Ph.D.