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oai:www.ideals.illinois.edu:2142/87081 2023-07-11 col_2142_5131 col_2142_16359 com_2142_5130 com_2142_16358 com_2142_234

Jacobson, Sheldon H. Hall, Shane Nikolaus 2015-09-28T15:37:19Z 2015-09-28T15:37:19Z 10000-01-01 2006 2006 The first problem models a general childhood immunization schedule to design a vaccine formulary that minimizes the cost of fully immunizing a child. The second problem models a general childhood immunization schedule to design a vaccine formulary that safely immunizes a child against several infectious diseases by restricting or limiting extraimmunization (i.e., extra doses of vaccine). These problems are vitally important since the cost of vaccinating a child contributes to the underimmunization of children, and extraimmunization poses biological risks, amplifies philosophical concerns with vaccination, and creates an unnecessary economic burden on society. These models are rigorously analyzed and several algorithms---both exact and heuristic---are presented. Furthermore, a computational comparison of these algorithms is presented for the 2006 Recommended Childhood Immunization Schedule as well as several randomly generated childhood immunization schedules. The third problem combines the first two problems by modeling a general childhood immunization schedule to design a vaccine formulary that minimizes the cost of fully immunizing a child while restricting or limiting extraimmunization. The results reported here provide both fundamental insights to the operations research community as well as practical value for the public health community. Made available in DSpace on 2015-09-28T15:37:19Z (GMT). No. of bitstreams: 2 license.txt: 4848 bytes, checksum: 96035ab3f5e1c23cc7138a224ce498bd (MD5) 3242861.pdf: 5047706 bytes, checksum: 21c47e7cc167badbfb088641791b34d5 (MD5) Previous issue date: 2006 Embargo set by: Seth Robbins for item 88362 Lift date: Forever Reason: Restricted to the U of I community idenfinitely during batch ingest of legacy ETDs Restricted to the U of I community idenfinitely during batch ingest of legacy ETDs U of I Only 143 p. Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 2006. http://hdl.handle.net/2142/87081 (MiAaPQ)AAI3242861 eng Health Sciences, Public Health The Design and Analysis of Pediatric Vaccine Formularies: Theory and Practice text Industrial Engineering Industrial Engineering University of Illinois at Urbana-Champaign Dissertation Ph.D.