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Philip F. Solter Biondo, Alexander Welker 2015-09-28T15:38:27Z 2015-09-28T15:38:27Z 10000-01-01 2003 2003 In conclusion, ANP and BNP are normally produced and stored in the atria. With HCM, significant peptide and mRNA expression of BNP is found in the ventricles, while protein and gene expression of ANP remains mainly in the atria. This pattern agrees with increases in plasma concentrations of both peptides in cats with HCM, and suggests that BNP may be a more sensitive and specific plasma marker of feline HCM than ANP. Endothelin is expressed and produced throughout the cardiac tissue. Although plasma concentrations of ET-1 are known to be significantly higher in feline HCM than normal cats, it is probably due to noncardiac sources. The lack of detectable vasopressin expression suggests that vasopressin is not produced in significant amounts in feline cardiac tissue, contrasting with previous studies performed in rats. Made available in DSpace on 2015-09-28T15:38:27Z (GMT). No. of bitstreams: 2 license.txt: 4848 bytes, checksum: 96035ab3f5e1c23cc7138a224ce498bd (MD5) 3101799.pdf: 5906432 bytes, checksum: e249613ef7b3900d5e25b48d9466ef02 (MD5) Previous issue date: 2003 Embargo set by: Seth Robbins for item 88406 Lift date: Forever Reason: Restricted to the U of I community idenfinitely during batch ingest of legacy ETDs Restricted to the U of I community idenfinitely during batch ingest of legacy ETDs U of I Only 140 p. Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 2003. http://hdl.handle.net/2142/87125 (MiAaPQ)AAI3101799 eng Biology, Veterinary Science Cardiac Vasoactive Peptides in Hypertrophic Cardiomyopathy of Cats text Veterinary Clinical Medicine Veterinary Clinical Medicine University of Illinois at Urbana-Champaign Dissertation Ph.D.