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oai:www.ideals.illinois.edu:2142/87620 2023-07-11 col_2142_5131 col_2142_25441 com_2142_5130 com_2142_25440 com_2142_14833

Vimr, Eric R. Ringenberg, Michael Alan 2015-09-28T16:21:35Z 2015-09-28T16:21:35Z 10000-01-01 2002 2002 In this study, adaptation of a previously described in vivo model of neuraminidase-induced glomerular injury is described in the rat. Information derived from the initial pilot studies has been used to formulate the hypothesis that loss of glomerular sialic acid, concomitant with functional glomerular damage, results in a re-sialylation event associated with sequentially increased levels of glomerular linkage-specific sialyltransferase transcript levels and activity. The results of these experiments provide insight into specific molecular responses of podocytes to injury, in addition to demonstrating the versatility of this animal model for descriptive and mechanistic studies regarding podocyte sialobiology. Made available in DSpace on 2015-09-28T16:21:35Z (GMT). No. of bitstreams: 2 license.txt: 4848 bytes, checksum: 96035ab3f5e1c23cc7138a224ce498bd (MD5) 3044208.pdf: 4775597 bytes, checksum: 35661a6884ffa1ced623ca0aa3b9a256 (MD5) Previous issue date: 2002 Embargo set by: Seth Robbins for item 88901 Lift date: Forever Reason: Restricted to the U of I community idenfinitely during batch ingest of legacy ETDs Restricted to the U of I community idenfinitely during batch ingest of legacy ETDs U of I Only 100 p. Thesis (Ph.D.)--University of Illinois at Urbana-Champaign, 2002. http://hdl.handle.net/2142/87620 (MiAaPQ)AAI3044208 eng Biology, Animal Physiology Molecular Responses to Desialylation in a Rat Model of Induced Glomerulopathy text Veterinary Pathobiology Veterinary Pathobiology University of Illinois at Urbana-Champaign Dissertation Ph.D.